Copyright 2007-8 University of British Columbia 

Jeremy K. Seamans

Associate Professor

Psychiatry, UBC

Ph.D. 1998, University of British Columbia

Canada Research Chair

Senior Scholar: Michael Smith Foundation for Health Research

Supported by: MSFHR, CIHR, TULA foundation, NIMH, NARSAD.


Publications

GoogleTM Scholar Searchhttp://scholar.google.ca/scholar?hl=en&lr=&client=firefox-a&scoring=r&q=seamans+jk&as_ylo=2007

Schizophrenia, attention deficit disorder and addiction are all are thought to involve abnormalities in the prefrontal cortex. The dopamine modulation of the prefrontal cortex helps to regulate attention as well as aid in the manipulation of information to plan forthcoming thoughts or actions. My lab studies active prefrontal cortex neurons and networks using a variety of techniques from recording the activity of single neurons to high-level computational analyses of networks of cells during the performance of complex cognitive tasks. Along with Dr. Daniel Durstewitz we developed a theory of how dopamine may shift network dynamics in the prefrontal cortex to alter information processing and cognition in normal and disease states. We are currently testing aspects of this theory with the hope that it may improve our understanding of the prefrontal cortex and how it is altered in schizophrenia and addiction.